NFL Schedule Announcement Kicks off Week 1 Wagering

BY RALPH VENTRE

The National Football League Schedule Release means Week 1 betting lines are on the board at sportsbooks around the country.

Hosting the Buffalo Bills in the NFL regular season opener on Thursday, September 8, the Super Bowl champion Los Angeles Rams sit as a marginal one-point favorite over the team that owns the lowest odds to win it all in 2022.

In the two other Week 1 primetime matchups, both visiting teams are favored.  The Tampa Bay Buccaneers opened as a 2.5-point road favorite over the Dallas Cowboys (Sunday Night Football) while Russell Wilson and the Denver Broncos are giving 4 points to the Seahawks on Monday night in Seattle.

The largest Week 1 game spread opened with the visiting Indianapolis Colts laying 7.5 points against the Houston Texans.

Three more games had at least 6 points separating the sides. The reigning AFC champion Cincinnati Bengals are 6.5-point home favorites against the division rival Pittsburgh Steelers. The San Francisco 49ers favored by 6.5 points in their battle with the Chicago Bears. The New York Giants are 6.5-point road underdogs against the Tennessee Titans.

All lines were taken from DraftKings Sportsbook app (New Jersey) on May 12.

Which Week 1 game are you most excited for?

📺: 2022 NFL Schedule Release — 8pm ET on @nflnetwork
🎟: https://t.co/mkOfStmInN pic.twitter.com/BO1CjGwufE

— NFL (@NFL) May 12, 2022

Week 1 Pro Football Lines
(courtesy DraftKings)

Buffalo Bills at Los Angeles Rams (-1; 52 o/u)

Baltimore Ravens (-4.5; 46 o/u) at New York Jets

Pittsburgh Steelers at Cincinnati Bengals (-6.5; 45 o/u)

Cleveland Browns (-3.5; 42.5 o/u) at Carolina Panthers

New Orleans Saints (-3.5; 42 o/u) at Atlanta Falcons

Philadelphia Eagles (-4; 46.5 o/u) at Detroit Lions

New England Patriots at Miami Dolphins (-3; 45 o/u)

San Francisco 49ers (-6.5; 42.5 o/u) at Chicago Bears

Indianapolis Colts (-7.5; 44.5 o/u) at Houston Texans

Jacksonville Jaguars at Washington Commanders (-4; 44.5 o/u)

Kansas City Chiefs (-3; 53 o/u) at Arizona Cardinals

New York Giants at Tennessee Titans (-6.5; 45 o/u)

Green Bay Packers (-1.5; 49 o/u) at Minnesota Vikings

Las Vegas Raiders at Los Angeles Chargers (-4; 52 o/u)

Tampa Bay Buccaneers (-2.5; 51.5 o/u) at Dallas Cowboys

Denver Broncos (-4; 41 o/u) at Seattle Seahawks